This article will break down the high-level overview of how software works in today’s world — and what all those terms mean that you probably often hear in conversations
When building an application developers can choose which tools and technologies to use for each part of the stack (remember the stack is the 3 pieces that make up the application: front-end, back-end, & the database).
When using the internet it’s easy to get lost in the magic of everything. Opening a browser, typing in a URL, and hitting enter brings you exactly where you want to be in a matter of seconds. Most people understand that there is a lot that goes on behind the scenes to make this possible, but feel too overwhelmed to even begin to try to understand it all. This article will help you understand what's really going on, and hopefully let you realize that grasping a high level overview of the system really isn’t as hard as you think!
"We make drugs that look like what your body would make itself," says Dr. Way. Epo is a naturally-occurring protein in the body which triggers red blood cell (RBC) production by binding to RBC stem cells in the bone marrow. The problem is that Epo in it's natural form can't tell the difference between an RBC stem cell or a platelet stem cell. If the dose is too high, it triggers the body to make too many platelets, causing blood clotting. Way and Burrill, along with other collaborators, designed a drug that is able to differentiate between stem cells, thereby removing the side effect. Here's how they did it.
If you're into the biosciences, you've heard about CRISPR. Clustered regularly interspaced short palindromic repeats (CRISPR) and its Cas9 nucleases were discovered as part of bacterial immune systems in the 1970s; only in 2012 were they refined into a powerful gene-editing technology. Previous gene-editing techniques required customized proteins for each gene sequence, an expensive and error-prone process. For CRISPR, changing a 20-nucleotide gRNA sequence is "ridiculously simple" and can be done online, says Medvedik.
Fundamentally, computing is a all about controlling and managing information over time. Brains can compute, and so can your smartphone. The information that flows through both is fundamentally the same. Today we’re starting with the most commonly-used basic unit of computing: the doped silicon transistor. And yes, like human types of doping, the silicon is doped with a little bit of something special that alters its normal behavior.